Serum heat-stable alkaline phosphatase activity in normal pregnancy.
East Afr Med J
; 76(6): 341-3, 1999 Jun.
Article
em En
| MEDLINE
| ID: mdl-10750523
ABSTRACT
OBJECTIVE:
To determine the reference values for heat-stable alkaline phosphatase in apparently healthy non-pregnant and in normal pregnant females and to assess the suitability of this parameter as a measure of placental function and indirectly as a measure of foetal survival.DESIGN:
A prospective study.SETTING:
Ante-natal clinic, University of Nigeria Teaching Hospital, Enugu, Nigeria.PARTICIPANTS:
Ninety eight apparently normal pregnant females in various gestational ages and 47 apparently healthy non-pregnant females. MAIN OUTCOMEMEASURES:
The serum heat-stable alkaline phosphatase activity.RESULTS:
Variability in values exists between individuals in the same gestational age. The mean and standard deviation of serum heat-stable alkaline phosphatase was found to be 0.79 +/- 1.54 iu/L in the control group. No significant difference was found (p < 0.05) between this and the mean and standard deviation of serum alkaline phosphatase of 0.98 +/- 1.28 iu/L found in the first eight weeks of gestation. However the means and standard deviations of first trimester, second and third trimester were significantly higher than the controls.CONCLUSION:
In the face of worsening economic situation in third world countries this simple method could be used in urban and some rural hospitals in assessing placenta insufficiency.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gravidez
/
Fosfatase Alcalina
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
País/Região como assunto:
Africa
Idioma:
En
Revista:
East Afr Med J
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Nigéria