New macrolides and furan carboxylic acid derivative from the sponge-derived fungus Cladosporium herbarum.
J Nat Prod
; 64(4): 527-30, 2001 Apr.
Article
em En
| MEDLINE
| ID: mdl-11325242
ABSTRACT
Bioassay-guided fractionation of organic extracts of Cladosporium herbarum, isolated from the marine sponge Callyspongia aerizusa, yielded two new macrolide metabolites pandangolide 3 and 4 (1 and 2) and the known fungal metabolites pandangolide 2 (3), cladospolide B (4), and iso-cladospolide B (5). Also isolated were the antimicrobially active (against Bacillus subtilis and Staphylococcus aureus) furan carboxylic acids Sumiki's acid (6) and its new derivative, acetyl Sumiki's acid (7). All structures were elucidated by spectroscopic methods.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cladosporium
/
Macrolídeos
/
Anti-Infecciosos
Limite:
Animals
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Alemanha