The reliability of plain radiography in experimental fracture healing.
Skeletal Radiol
; 30(3): 151-6, 2001 Mar.
Article
em En
| MEDLINE
| ID: mdl-11357453
ABSTRACT
OBJECTIVE:
To investigate the reliability of radiographs in the evaluation of healing of closed fractures.DESIGN:
A closed midshaft tibial fracture was created in 40 goats and stabilized with an external fixator. The animals were assigned to four groups no injection, injection of 1 mg osteogenic protein-1 (OP-1), 1 mg OP-1 with collagenous carrier, or carrier alone. Radiographs were performed weekly until the animals were killed after 2 and 4 weeks. Healing was evaluated using radiographs, biomechanical testing, and histological examination. All radiographs were examined by two independent observers. Interobserver agreement was calculated and radiographic scores were compared with mechanical and histological scores using regression analysis.RESULTS:
Regression analysis showed poor correlation between radiographic scores and biomechanical and histological data. Correlation coefficients varied between 0.39 and 0.63. Good agreement between the observers was seen in only three parameters visibility of the fracture line, weightbearing ability, and a combined healing parameter.CONCLUSION:
Plain radiography provides poor parameters for monitoring the fracture healing process.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fraturas da Tíbia
/
Fator de Crescimento Transformador beta
/
Consolidação da Fratura
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Skeletal Radiol
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Holanda