Plasmapheresis in the treatment of ataxic sensory neuropathy associated with Sjögren's syndrome.
Eur Neurol
; 45(4): 270-4, 2001.
Article
em En
| MEDLINE
| ID: mdl-11385268
ABSTRACT
Sjögren's syndrome (SS) is an important but poorly recognized cause of peripheral neuropathy. Several forms of peripheral nerve dysfunction occur, including trigeminal sensory neuropathy, mononeuropathy multiplex, distal sensorimotor polyneuropathy and pure sensory neuronopathy. The pathological findings vary and the definite treatment is not known. Here we present 4 cases of acute ataxic sensory polyneuropathy with SS, and the experience of treatment with plasmapheresis (PP). The 4 patients were all females; ages ranged from 30 to 58 years. All had prominent loss of kinesthetic and proprioceptive sensation. The course ranged from acute to subacute onset. Patients were treated with 5-9 sessions of PP. Two patients with initiation of treatment within 2 weeks of onset showed dramatic and sustained responses after PP, while the other 2 had no detectable effects. Our experience showed that PP should be considered in patients who present with sensory neuropathy associated with SS, and the treatment should be given as early as possible.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ataxia
/
Neuropatia Hereditária Motora e Sensorial
/
Síndrome de Sjogren
/
Plasmaferese
/
Transtornos de Sensação
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur Neurol
Ano de publicação:
2001
Tipo de documento:
Article