[The enhancing effects of arginine-vasopressin on antibody level and lymphocyte proliferation of rats].
Sheng Li Xue Bao
; 51(4): 435-8, 1999 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-11498973
ABSTRACT
The effects of arginine-vasopressin (AVP) on some immune parameters of rats were studied by using icv of AVP. The hemolysin to sheep red blood cell and IgG production were enhanced by icv of 100, 800 ng AVP. Both the actions were partly blocked by icv preinjection of the V1 receptor antagonist DPAVP. It was also found that the NE and corticosterone levels in the serum of rats were significantly reduced after icv of AVP. The above results suggest that AVP executes immunofunctions through V1 receptors in the paraventricular nucleus of the brain. Considering our previous results, the AVP enhanced immunofunction may be related to its inhibition of corticotropin releasing factor release or the excitatory activity of sympathetic nerves.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina G
/
Arginina Vasopressina
/
Ativação Linfocitária
Limite:
Animals
Idioma:
Zh
Revista:
Sheng Li Xue Bao
Ano de publicação:
1999
Tipo de documento:
Article