Excretion of miserotoxin and detoxification of the aglycone by grasshoppers (Orthoptera: Acrididae).
Phytochemistry
; 58(5): 739-42, 2001 Nov.
Article
em En
| MEDLINE
| ID: mdl-11672738
ABSTRACT
Two species of grasshoppers (Melanoplus bivittatus and M. sanguinipes) tolerated high levels of miserotoxin (3-nitro-1-propyl-beta-D-glucopyranoside) in their diet. Miserotoxin is a causative agent in cattle poisoning when timber milkvetch (Astragalus miser) is consumed. Toxic effects were averted by grasshoppers in part by excretion of the intact glycoside. When the aglycone was administered, detoxification was achieved by two routes by oxidation of the aglycone to 3-nitropropionic acid which was then conjugated with glycine, and by glucosylation of the aglycone to miserotoxin, in each case followed by excretion.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Propionatos
/
Doxorrubicina
/
Glucosídeos
/
Glicina
/
Gafanhotos
Limite:
Animals
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Canadá