Effect of the distal-balloon protection system on microembolization during carotid stenting.
Circulation
; 104(17): 1999-2002, 2001 Oct 23.
Article
em En
| MEDLINE
| ID: mdl-11673335
ABSTRACT
BACKGROUND:
The distal-balloon protection system is being evaluated for its efficacy in preventing embolic neurological events during carotid stenting (CAS). We sought to determine the effect of this system on the frequency of Doppler-detected microembolic signals (MES) during CAS. METHODS ANDRESULTS:
Using transcranial Doppler, we compared the frequency of MES during CAS in 2 groups 39 patients without distal protection and 37 who used the distal-balloon protection system (GuardWire). There were no significant differences in the clinical or angiographic characteristics between the 2 groups. Three phases with increased MES counts were identified during unprotected CAS; these were stent deployment, predilation, and postdilation (75+/-57, 32+/-36, and 27+/-25 METS, respectively). The distal-balloon protection significantly reduced the frequency of MES during CAS (MES counts 164+/-108 in the control versus 68+/-83 in the protection group; P=0.002), particularly during these 3 phases. MES in the protection group were detected predominantly during sheath placement, guidewire manipulation, and distal-balloon deflation.CONCLUSION:
Three phases with increased MES counts were identified during unprotected CAS (eg, stent deployment, predilation, and postdilation). The distal-balloon protection system significantly reduced the frequency of MES during CAS, particularly during these 3 phases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cateterismo
/
Doenças das Artérias Carótidas
/
Stents
/
Implante de Prótese Vascular
/
Embolia Intracraniana
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Circulation
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Estados Unidos