Myocardial perfusion correlates with improvement of systolic function of the left ventricle after CABG. Dobutamine echocardiography and Tc-99m-MIBI SPECT study.
Eur J Cardiothorac Surg
; 21(1): 32-5, 2002 Jan.
Article
em En
| MEDLINE
| ID: mdl-11788252
ABSTRACT
OBJECTIVE:
The aim of the study was to assess the effect of surgical revascularization [coronary artery bypass grafting (CABG)] on systolic function and perfusion of the left ventricle using dobutamine echocardiography (DE) and Tc-99m-MIBI SPECT (SPECT).METHODS:
There were 32 patients mean age 52.2+/-7.2 years in whom DE and SPECT were performed before and 3-4 months after CABG using standard protocols. Wall motion score index (WMSI) and perfusion index (PI) were calculated.RESULTS:
Significant improvement of WMSI at rest (1.44+/-0.46 vs 1.33+/-0.41; P=0.03) as well as after maximal dose of dobutamine (1.49+/-0.42 vs 1.39+/-0.44; P=0.02) was observed after CABG as compared to preoperative examination. Similar relation was observed during SPECT study. Perfusion index diminished significantly after revascularization during rest acquisition (2.19+/-0.71 vs 1.93+/-0.70; P=0.0008) and after Dipirydamole administration (2.73+/-0.73 vs 2.20+/-0.69; P=0.0001) as compared to preoperative examination. We found correlation between PI and WMSI at rest before CABG (R=0.46; P=0.01), PI after Dipirydamole and WMSI after maximal dose of Dobutamine before CABG (R=0.37; P=0.04), PI and WMSI at rest after CABG (R=0.39; P=0.03), PI after Dipirydamole and WMSI after dobutamine after CABG (R=0.38; P=0.03).CONCLUSIONS:
Surgical revascularization significantly improves both perfusion and contractility. Increased perfusion after CABG correlates with improvement of systolic function of the left ventricle.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sístole
/
Reperfusão Miocárdica
/
Ponte de Artéria Coronária
/
Função Ventricular Esquerda
/
Doença das Coronárias
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Aged
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur J Cardiothorac Surg
Assunto da revista:
CARDIOLOGIA
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Polônia