Characterization of structure and diffusion behaviour of Ca-alginate beads prepared with external or internal calcium sources.
J Microencapsul
; 19(6): 775-82, 2002.
Article
em En
| MEDLINE
| ID: mdl-12569026
ABSTRACT
Ca-alginate beads were prepared with either external or internal calcium sources. The structures of both beads were investigated with the aid of scanning electron microscopy (SEM) and confocal microscopy. It was shown that the beads with internal calcium source had a looser structure and bigger pore size than those with external calcium source. The attempts to interpret the difference were carried out by determining the Ca content within the beads at various times, which indicated that it was the different gelation mechanisms that caused the difference of structures of both beads. Furthermore, it was also found that the diffusion rate of haemoglobin (Hb) within the beads with an internal calcium source was faster than that of the beads with an external one, which was consistent with the observation of their structures.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cápsulas
/
Composição de Medicamentos
Idioma:
En
Revista:
J Microencapsul
Assunto da revista:
FARMACIA
Ano de publicação:
2002
Tipo de documento:
Article