An endogenous peptide is involved in internal control of metamorphosis in the marine invertebrate Cassiopea xamachana (Cnidaria: Scyphozoa).
Dev Genes Evol
; 213(2): 97-101, 2003 Mar.
Article
em En
| MEDLINE
| ID: mdl-12632179
ABSTRACT
In the metagenetic life-cycle of the scyphozoan Cassiopea xamachana metamorphosis of planula-larvae or larva-like buds to polyps is triggered by specific external cues which are transmitted inside the larva or bud where internal signals finally coordinate the initiation of metamorphosis. This study deals with an endogenous metamorphosis inducer present in planulae and buds of Cassiopea. The inductive cue is localized in the basal part of the buds and can be characterized as a peptide with an apparent molecular weight of about 7,000 Da. Further purification was performed via reversed phase HPLC on a C18 column. Additional inhibitor assays revealed that protein kinase C and PI3 kinase, two known elements of the metamorphosis-inducing signal transduction cascade in Cassiopea, may act downstream of the endogenous inducing peptide.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Transdução de Sinais
/
Cifozoários
/
Metamorfose Biológica
Limite:
Animals
Idioma:
En
Revista:
Dev Genes Evol
Assunto da revista:
BIOLOGIA
/
EMBRIOLOGIA
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Alemanha