Implantation of p(HEMA)-collagen composite into bone.
Biomaterials
; 13(9): 639-42, 1992.
Article
em En
| MEDLINE
| ID: mdl-1391411
ABSTRACT
The replacement of bone defects is very important in clinical practice. This study compares biological properties of poly(2-hydroxyethyl methacrylate)-collagen composite with those exhibited by pure p(HEMA), an insoluble fraction of calf skin collagen (ISC-40) and demineralized bone matrix after implantation into pig or dog femurs. The levels of biodegradation or destruction of implants and healing of bone defects were studied using X-ray photography, histology and enzyme histochemistry. The results indicated a significant effect of collagen on biological destruction of the p(HEMA)-composite implants; even a minute amount of collagen influences this process dramatically. A stimulatory action of collagen on new bone formation may be of importance in bone defect healing.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poli-Hidroxietil Metacrilato
/
Próteses e Implantes
/
Materiais Biocompatíveis
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Osso e Ossos
/
Colágeno
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Biomaterials
Ano de publicação:
1992
Tipo de documento:
Article