Effect of oxiracetam on scopolamine-induced amnesia in the rat in a spatial learning task.
Pharmacol Biochem Behav
; 43(3): 949-51, 1992 Nov.
Article
em En
| MEDLINE
| ID: mdl-1448491
ABSTRACT
The effects of the nootropic agent 4-hydroxy-2-oxopyrrolidinoacetamide (oxiracetam) on memory and performance impairments induced by scopolamine were evaluated in the Morris water maze task. No effect was seen on the performance of rats when treated with oxiracetam (30 mg/kg, IP) alone. Task performance of scopolamine (0.2 mg/kg, SC)-treated rats was impaired as compared to that of control animals. The behavioral deficits expressed in the task by scopolamine treatment were attenuated by the same dose of oxiracetam.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psicotrópicos
/
Pirrolidinas
/
Escopolamina
/
Percepção Espacial
/
Aprendizagem
/
Memória
Limite:
Animals
Idioma:
En
Revista:
Pharmacol Biochem Behav
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Itália