Cytotoxic constituents of the fruit body of Daedalea dickisii.
J Nat Prod
; 68(6): 911-4, 2005 Jun.
Article
em En
| MEDLINE
| ID: mdl-15974617
ABSTRACT
Three new lanostane triterpenoids (1, 7, 8) and five new lanostane triterpene glucosides (2-6) have been isolated from the fruit bodies of Daedalea dickinsii. Their structures were established primarily by NMR experiments, and their biological activity against HL-60 and HCT-15 cell lines was investigated. Compounds 3-6 induced internucleosomal DNA fragmentation characteristic of apoptotic cell death in the HL-60 cell line.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polyporaceae
/
Triterpenos
/
Glucosídeos
/
Lanosterol
/
Antineoplásicos
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Japão
