Latent tuberculosis infection: risks to health care students at a hospital in Lima, Peru.
Int J Tuberc Lung Dis
; 10(10): 1146-51, 2006 Oct.
Article
em En
| MEDLINE
| ID: mdl-17044209
ABSTRACT
SETTING:
University hospital and university campus in Lima, Peru.OBJECTIVE:
To demonstrate the risk of latent tuberculosis infection (LTBI) in the hospital relative to the community.DESIGN:
Prospective cohort study of university students measuring prevalence, boosting, and conversion of tuberculin skin tests (TSTs) among health care students (HCS) and non-health care students (NHCS).RESULTS:
Among the HCS relative to NHCS, prevalence of initial positive TST was 20.9% vs. 12.2% (P < 0.001), and conversion rate was 1.1% vs. 0% (P = 0.423) at the 10 mm cut-off and 11.8% vs. 0% at the 6 mm cut-off (P = 0.00005). Multivariate analysis showed that the HCS group had a higher risk of baseline positive TST compared with the NHCS group after controlling for confounding factors (OR 1.7, 95% CI 1.1-2.6).CONCLUSION:
HCS are at greater risk than NHCS for having positive baseline TSTs and for TST conversion at the 6 mm cut-off. We conclude that the hospital we studied in Lima, Peru, poses a greater risk than the surrounding community for tuberculosis infection, and greater attention to hospital infection control measures is warranted. A higher rate of skin test boosting among the HCS cohort suggests the possibility of transient, non-progressive LTBI, which merits further study.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
2_ODS3
/
3_ND
/
4_TD
Problema de saúde:
2_enfermedades_transmissibles
/
3_neglected_diseases
/
3_tuberculosis
/
4_tuberculosis
Assunto principal:
Estudantes de Medicina
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Estudantes de Enfermagem
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Tuberculose
/
Infecção Hospitalar
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
America do sul
/
Peru
Idioma:
En
Revista:
Int J Tuberc Lung Dis
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Estados Unidos