Myasthenia gravis exacerbation or unmasking associated with telithromycin treatment.
Neurology
; 67(12): 2256-8, 2006 Dec 26.
Article
em En
| MEDLINE
| ID: mdl-17065592
ABSTRACT
Telithromycin, a new ketolide antibiotic, has been implicated in the exacerbation or unmasking of myasthenia gravis. This retrospective study presents two clinical reports and summarizes eight other suspected cases notified to the French pharmacovigilance system, highlighting a potentially life-threatening risk of telithromycin treatment in myasthenic patients. An important common feature was that, in seven cases, symptomatology occurred within 2 hours of first telithromycin intake--notably in cases of severe exacerbation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cetolídeos
/
Miastenia Gravis
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Neurology
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
França