K-complex-induced seizures in autosomal dominant nocturnal frontal lobe epilepsy.
Clin Neurophysiol
; 119(10): 2201-4, 2008 Oct.
Article
em En
| MEDLINE
| ID: mdl-18762450
ABSTRACT
OBJECTIVE:
To examine in detail the relations between seizures and K-complexes in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE).METHODS:
Prolonged continuous video-EEG recording and analysis of 30 seizures in an 18-year-old woman suffering from ADNFLE with a CHRNA4 gene mutation.RESULTS:
Twenty-seven of 30 recorded seizures started just after a K-complex. In nine cases a sound induced a K-complex that was immediately followed by the seizure. Most seizures preceded repetitive and brief ictal restarts.CONCLUSIONS:
Three new characteristics have been observed in this ADNFLE patient a K-complex is almost invariably present at seizure onset; sounds trigger some seizures; ictal restarts occur often.SIGNIFICANCE:
These new observations--the presence of K-complexes at seizure onset and occurrence of sound-triggered seizures--support the view that ADNFLE seizures may be initiated by K-complexes.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ritmo Circadiano
/
Epilepsia do Lobo Frontal
/
Eletroencefalografia
/
Genes Dominantes
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Clin Neurophysiol
Assunto da revista:
NEUROLOGIA
/
PSICOFISIOLOGIA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
França