Insulin analogues: fears, facts and fantasies.
Diabetes Metab Res Rev
; 25(1): 50-1, 2009 Jan.
Article
em En
| MEDLINE
| ID: mdl-19145585
ABSTRACT
IGF-I and insulin, acting through both IGF-I and insulin receptors, have been studied widely to evaluate their oncogenic and teratogenic properties. These two properties need to be studied for each new insulin analogue, in addition to measurements of their metabolic and pharmacodynamic features. This editorial critiques a study in this issue of the journal of several insulin analogues in their action in vitro on several cancer-related cell lines. The conclusions and limitations of these studies are highlighted, especially as they influence guidelines for using these analogues patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Insulina
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Diabetes Metab Res Rev
Assunto da revista:
ENDOCRINOLOGIA
/
METABOLISMO
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Itália