Functional cartilage MRI T2 mapping: evaluating the effect of age and training on knee cartilage response to running.
Osteoarthritis Cartilage
; 18(3): 358-64, 2010 Mar.
Article
em En
| MEDLINE
| ID: mdl-19948266
ABSTRACT
OBJECTIVE:
To characterize effects of age and physical activity level on cartilage thickness and T2 response immediately after running.DESIGN:
Institutional review board approval was obtained and all subjects provided informed consent prior to study participation. Cartilage thickness and magnetic resonance imaging (MRI) T2 values of 22 marathon runners and 15 sedentary controls were compared before and after 30 min of running. Runner and control groups were stratified by ageRESULTS:
After running MRI T2 values decreased in superficial femoral (2 ms-4 ms) and tibial (1 ms-3 ms) cartilage along with a decrease in cartilage thickness (femoral 4%-8%, tibial 0%-12%). Smaller decrease in cartilage T2 values were observed in the middle zone of cartilage, and no change was observed in the deepest layer. There was no difference cartilage deformation or T2 response to running as a function of age or level of physical activity.CONCLUSIONS:
Running results in a measurable decrease in cartilage thickness and MRI T2 values of superficial cartilage consistent with greater compressibility of the superficial cartilage layer. Age and level of physical activity did not alter the T2 response to running.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Corrida
/
Exercício Físico
/
Cartilagem Articular
/
Osteoartrite do Joelho
/
Articulação do Joelho
Limite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Osteoarthritis Cartilage
Assunto da revista:
ORTOPEDIA
/
REUMATOLOGIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos