Comparison of antigenuria after immunization with three Haemophilus influenzae type b conjugate vaccines.
Pediatr Infect Dis J
; 10(4): 311-4, 1991 Apr.
Article
em En
| MEDLINE
| ID: mdl-2062627
ABSTRACT
The incidence of antigenuria was documented after vaccination of 75 children 15 to 60 months of age with one of three Haemophilus influenzae type b conjugate vaccines, PRP-D (ProHIBiT), PRP-T and HbOC (HibTITER). Unconcentrated and concentrated urine was tested on the first, third, fifth and seventh days after vaccination. Antigenuria occurred on Day 1 in 100% of PRP-D, 43% of PRP-T and 12% of HbOC recipients. The percentages of children excreting antigen on Day 3 were 95, 17 and 8%; on Day 5 they were 36, 4 and 12%; and on Day 7 they were 14, 0 and 18% for PRP-D, PRP-T and HbOC, respectively. The difference in the occurrence of antigenuria resulting from each vaccine was statistically significant on Day 1 and for PRP-D compared with PRP-T or HbOC on Day 3. It is important for clinicians to be aware of the frequency with which antigenuria occurs after these vaccines so that appropriate therapeutic decisions can be made.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
2_ODS3
/
3_ND
/
4_TD
Problema de saúde:
2_enfermedades_transmissibles
/
3_zoonosis
/
4_meningitis
Assunto principal:
Proteínas de Bactérias
/
Vacinas Bacterianas
/
Toxoide Diftérico
/
Toxoide Tetânico
/
Haemophilus influenzae
/
Vacinas Anti-Haemophilus
/
Antígenos de Bactérias
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Child, preschool
/
Humans
/
Infant
Idioma:
En
Revista:
Pediatr Infect Dis J
Assunto da revista:
DOENCAS TRANSMISSIVEIS
/
PEDIATRIA
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Panamá