Serum levels of long pentraxin PTX3 in patients with polymyalgia rheumatica.
Clin Exp Rheumatol
; 28(5): 756-8, 2010.
Article
em En
| MEDLINE
| ID: mdl-20822713
ABSTRACT
OBJECTIVES:
To evaluate PTX3 feasibility to provide a prognostic tool in PMR clinical practice.METHODS:
Circulating PTX3 levels were measured in 93 PMR patients at disease onset and during corticosteroid therapy and in 46 normal controls (NC) by ELISA.RESULTS:
No difference in PTX3 concentrations was observed between NC and PMR either at disease onset and during follow-up or between groups of patients defined according to the presence of recurrence/relapse.CONCLUSIONS:
PTX3 serum levels do not increase significantly in active PMR. Further studies on patients with giant-cell arteritis could evaluate whether large vessel involvement may be associated to increased PTX3 levels.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polimialgia Reumática
/
Proteína C-Reativa
/
Componente Amiloide P Sérico
/
Glucocorticoides
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Clin Exp Rheumatol
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Itália