Prognosis of gingival squamous cell carcinoma diagnosed after invasive procedures.
Asian Pac J Cancer Prev
; 12(10): 2649-52, 2011.
Article
em En
| MEDLINE
| ID: mdl-22320968
ABSTRACT
Gingival squamous cell carcinoma (SCC) has a relatively poor prognosis, because differential diagnoses of periodontitis and osteomyelitis are difficult to exclude. As such, gingival SCC is usually diagnosed late, following invasive procedures such as extraction or curettage. The purpose of this study was to classify gingival SCC patients into two groups according to the location of their primary lesion dentate and edentulous, and to determine the appropriate treatment strategy by comparing clinical and histological features as well as treatment results. The medical records of 76 patients diagnosed with gingival SCC and treated at one institute from 1 January 1993 to 31 December 2007 were reviewed. The overall 5-year survival rate was 60.7%, and the mean survival was 98 months. Factors affecting survival included bone invasion of the primary lesion (p = 0.035), neck node metastasis (p = 0.001), and local recurrence (p = 0.000). The results suggest that more aggressive treatment, such as setting a broad surgical field and enforcing preventive neck dissection, can improve outcome, although they are associated with increased rate of cancer bone invasion and neck metastasis in patients diagnosed with cancer after receiving invasive procedures.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
6_ODS3_enfermedades_notrasmisibles
Problema de saúde:
6_mouth_oropharynx_cancers
/
6_oral_conditions_disorders
Assunto principal:
Neoplasias Gengivais
/
Carcinoma de Células Escamosas
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Asian Pac J Cancer Prev
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2011
Tipo de documento:
Article