A novel t(3;8)(p13;q21.1) translocation in a case of lipoblastoma.
Pediatr Surg Int
; 28(7): 737-40, 2012 Jul.
Article
em En
| MEDLINE
| ID: mdl-22488564
ABSTRACT
Lipoblastoma is a rare benign neoplasm of embryonic white fatty tissue primarily found in the extremities of children <3 years old (Batanian et al., Cancer Genet Cytogenet 125(1)10-13, 2001; McVay MR et al., J Pediatr Surg 41(6)1067-1071, 2006; Kamal et al., J Pediatr Surg 46(7)E9-E12, 2011). Translocations affecting the 8q11-13 region are commonly reported with lipoblastoma and proper diagnosis requires cytogenetic analysis to distinguish it from malignant myxoid liposarcoma (Miller et al., J Pediatr Surg 32(12)1771-1772, 1997; Morerio et al., Pediatr Blood Cancer 52(1)132-134, 2009). We describe an additional case of lipoblastoma containing a new translocation t(3;8)(p13;q21.1), which has not previously been reported in a healthy asymptomatic child.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
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Cromossomos Humanos Par 8
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Lipoblastoma
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
Limite:
Child, preschool
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Female
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Humans
Idioma:
En
Revista:
Pediatr Surg Int
Assunto da revista:
PEDIATRIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Estados Unidos