Effect of physiological exercise on osteocalcin levels in subjects with adrenal incidentaloma.
J Endocrinol Invest
; 35(4): 357-8, 2012 Apr.
Article
em En
| MEDLINE
| ID: mdl-22652825
ABSTRACT
AIM:
In the present study, we have evaluated whether physical exercise affect low osteocalcin concentrations observed in patients with subclinical hypercortisolism. SUBJECTS ANDMETHODS:
Sixteen patients (10 men and 6 women, age 38-55 yr) with adrenal incidentaloma were studied. Fifteen healthy volunteers matched for age (range 35-47 yr) were used as controls. Subjects were submitted to a 8-week exercise-training program with cycle-ergometer for 1 h/day 3-4 days/week at 60% of their individual VO2 max. Before and after this period, resting venous serum osteocalcin and GH concentrations were measured in the same batch. The blood sampling after 8 weeks of the training program were performed after resting for one day. All patients and controls underwent also the following endocrine evaluation serum cortisol, plasma ACTH.RESULTS:
Our results demonstrate a significant increase of osteocalcin after physical exercise and a positive correlation between osteocalcin and GH. This later might suggest a role of GH in the increased osteocalcin secretion.CONCLUSIONS:
The data of the present study suggest a positive effect of physical exercise on bone metabolism in patients with adrenal incidentaloma.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Exercício Físico
/
Osteocalcina
/
Neoplasias das Glândulas Suprarrenais
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Endocrinol Invest
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Itália