Skin sealant InteguSeal® has no impact on prevention of postoperative mediastinitis after cardiac surgery.
J Hosp Infect
; 81(4): 278-82, 2012 Aug.
Article
em En
| MEDLINE
| ID: mdl-22705297
ABSTRACT
BACKGROUND:
Surgical site infections (SSIs) after median sternotomy represent a serious complication and a high potential risk for adverse clinical outcome after cardiac surgery. The antimicrobial skin sealant InteguSeal® was introduced as a novel tool in preventing development of SSI.AIM:
This single-centre investigation used two prospective registries to evaluate the prophylactic effect of a cyanoacrylate-based antimicrobial skin sealant (InteguSeal®) on the incidence of postoperative mediastinitis or any other form of chest skin incision SSI after elective cardiac surgery.METHODS:
Between October 2010 and April 2011 a total of 998 patients underwent elective cardiac surgical procedures with median sternotomy in our centre. In 496 patients InteguSeal® was included in standard preoperative preparation procedures before chest skin incision (group 1). In 502 patients standard preoperative skin preparation procedures were used without InteguSeal® (group 2). Freedom from mediastinitis and from any other form of SSI within 30 postoperative days were the primary and secondary endpoints, respectively.FINDINGS:
A total of 983 patients were eligible for inclusion in per-protocol analysis (488 vs 495 patients). The incidence of postoperative mediastinitis was 2.3% in group 1 vs 3.2% in group 2 (not significant). The incidence of any form of SSI was 10.9% in group 1 vs 11.5% in group 2 (not significant). Perioperative patient characteristics, complexity of surgical procedures performed and length of hospitalization were similar in both groups.CONCLUSION:
The use of InteguSeal® has no influence on the incidence of postoperative SSI and mediastinitis after cardiac surgery with median sternotomy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
2_ODS3
Problema de saúde:
2_muertes_prematuras_enfermedades_notrasmisibles
Assunto principal:
Infecção da Ferida Cirúrgica
/
Cirurgia Torácica
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Adesivos Teciduais
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Mediastinite
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Anti-Infecciosos Locais
Tipo de estudo:
Guideline
/
Incidence_studies
/
Prognostic_studies
Limite:
Aged
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Hosp Infect
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Alemanha