Improved antibacterial activity of cephalosporins loaded in magnetic chitosan microspheres.
Int J Pharm
; 436(1-2): 201-5, 2012 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-22732671
ABSTRACT
During the present study, we have evaluated magnetic chitosan as a potential drug delivery device, by specifically determining if chitosan could elute antibiotics in an active form that would be efficacious in inhibiting Staphylococcus aureus and Escherichia coli growth. We have demonstrated that the incorporation of cephalosporins of second, third and fourth generation into magnetic chitosan microspheres can possibly lead to an improved delivery of antibiotics in active forms, probably due to the inherent properties of chitosan.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
3_ND
Problema de saúde:
3_neglected_diseases
/
3_zoonosis
Assunto principal:
Cefalosporinas
/
Sistemas de Liberação de Medicamentos
/
Quitosana
/
Antibacterianos
Idioma:
En
Revista:
Int J Pharm
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Romênia