Peptides as therapeutics with enhanced bioactivity.
Curr Med Chem
; 19(26): 4451-61, 2012.
Article
em En
| MEDLINE
| ID: mdl-22830348
ABSTRACT
The development of techniques for efficient peptide production renewed interest in peptides as therapeutics. Numerous modifications for improving stability, transport and affinity profiles now exist. Several new adjuvant and carrier systems have also been developed, enhancing the immunogenicity of peptides thus allowing their development as vaccines. This review describes the established and experimental approaches for manufacturing peptide drugs and highlights the techniques currently used for improving their drug like properties.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Med Chem
Assunto da revista:
QUIMICA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Austrália