Mesoporous zirconia thin films with three-dimensional pore structures and their application to electrochemical glucose detection.
ACS Appl Mater Interfaces
; 5(9): 3599-606, 2013 May.
Article
em En
| MEDLINE
| ID: mdl-23566226
ABSTRACT
Mesoporous zirconia thin films (MZFs) were synthesized using zirconium hydroxide sol particles and a structure directing agent, Pluronic F127 (PEO106PPO70PEO106, EO = ethylene oxide, PO = propylene oxide). By controlling the F127/Zr ratio, we obtained two distinct MZFs with one in the Fmmm structure and the other in the P63/mmc structure. The pore structures of these films were characterized by low-angle X-ray diffraction, grazing incidence small-angle X-ray scattering, electron microscopy, and N2 sorption measurement. The Fmmm structure has interconnected pores and the P63/mmc structure has less accessible pores. The MZFs were functionalized with glucose oxidase (GOx) and were studied for their potentials as an electrochemical sensor for glucose. The GOx-functionalized MZF electrodes show high sensitivity to glucose in a broad range of glucose concentration of 0.025 - 6.8 mM, which can be attributed to their biocompatibility providing a favorable microenvironment for GOx immobilization and to their 3D pore structures with good accessibility of pores.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Zircônio
/
Nanoestruturas
/
Técnicas Eletroquímicas
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Glucose
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Hidróxidos
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
ACS Appl Mater Interfaces
Assunto da revista:
BIOTECNOLOGIA
/
ENGENHARIA BIOMEDICA
Ano de publicação:
2013
Tipo de documento:
Article