Diffusion-weighted MR imaging of benign and malignant breast lesions before and after contrast enhancement.
Rofo
; 186(2): 130-5, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-23929263
ABSTRACT
PURPOSE:
Many publications describe the use of diffusion-weighted imaging (DWI) in breast MRI. This article addresses the question of when to apply the DWI sequence in the course of the scan protocol. The effect of T1-shortening contrast media (CM) on the ADC values of breast lesions is investigated. MATERIALS ANDMETHODS:
Data were acquired on a 1.5âT scanner. 60 patients with 79 lesions (20 benign, 59 malignant) were included. The DWI sequence (4âmm slice thickness, b-values 50, 400, 800) was applied before and after CM administration. Before calculating the ADC map, the b50, b400 and b800 series were analyzed concerning lesion displacement. ADC values before and after CM application were compared.RESULTS:
The mean lesion size was 1.5â±â0.8âcm. On the basis of the b50 and b400 measurements, the mean ADC value of benign lesions was 1.89â± 0.30â×â10-3âmm2/s before and 1.85â±â0.28â×10-3 mm2/s after CM administration. The consecutive values for two pure mucinous carcinomas were 1.88â×â10-3âmm2/s and 1.81â×â103âmm2/s and for the remaining malignant lesions 1.00â±â0.18â×â10-3 mm2/s and 0.88â±â0.21â×â10-3âmm2. On the basis of the b50, b400 and b800 measurements, the mean ADC value of benign lesions was 1.99â± 0.37â×â10-3âmm2/s before and 1.97â±â0.30â×â10-3âmm2/s after CM application, whereas the mean ADC value of the malignant lesions was 0.90â±â0.14â×â10-3âmm2/s before and 0.80â±â0.14â×â10-3âmm2/s after CM application. While there was no significant change for benign lesions, the ADC value decrease in post-contrast malignant lesions was highly significant.CONCLUSION:
DWI after CM is possible and even leads to slightly better lesion discrimination between benign and malignant. However, further studies need to be performed to verify this. Citation Format â¢âJanka R, Hammon M, Geppert C etâal. Diffusion-Weighted MR Imaging of Benign and Malignant Breast Lesions Before and After Contrast Enhancement. Fortschr Röntgenstr 2014; 186 130â-â135.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
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Neoplasias da Mama
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Aumento da Imagem
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Imagem de Difusão por Ressonância Magnética
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
Rofo
Ano de publicação:
2014
Tipo de documento:
Article