[HIV testing: the medical laboratory role in HIV diagnosis and monitoring].
Harefuah
; 152(8): 477-80, 498, 2013 Aug.
Article
em He
| MEDLINE
| ID: mdl-24167934
ABSTRACT
Diagnosis of HIV infection is performed via enzyme immunoassay (EIA), an assay based on screening for antibodies against HIV. Confirmation of diagnosis is performed by Western-Blot, a more specific assay directed at a number of viral proteins for which antibodies exist. Routine follow-up of HIV-infected individuals includes measurement of CD4 cell count to evaluate the immune status, of viral load to assess virus replication, and of changes in the viral genome to characterize resistance to drugs and tropism. In addition, absence of the HLA B*5701 allele is verified before prescription of abacavir, and drug levels of protease-inhibitors are determined in treatment-failing individuals after ruling out other causes of failure. Rapid diagnosis and regular follow-up improve the quality of life of patients and extend their life expectancy, also helping to control the spread of the epidemic at the national level.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
2_ODS3
Problema de saúde:
2_enfermedades_transmissibles
Assunto principal:
Infecções por HIV
/
Técnicas Imunoenzimáticas
/
Contagem de Linfócito CD4
Tipo de estudo:
Diagnostic_studies
Aspecto:
Patient_preference
Limite:
Humans
Idioma:
He
Revista:
Harefuah
Ano de publicação:
2013
Tipo de documento:
Article