Secondary neutron doses in proton therapy treatments of ocular melanoma and craniopharyngioma.
Radiat Prot Dosimetry
; 161(1-4): 363-7, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-24222710
ABSTRACT
Monte Carlo simulations were used to assess secondary neutron doses received by patients treated with proton therapy for ocular melanoma and craniopharyngioma. MCNPX calculations of out-of-field doses were done for â¼20 different organs considering realistic treatment plans and using computational phantoms representative of an adult male individual. Simulations showed higher secondary neutron doses for intracranial treatments, â¼14 mGy to the salivary glands, when compared with ocular treatments, â¼0.6 mGy to the non-treated eye. This secondary dose increase is mainly due to the higher proton beam energy (178 vs. 75 MeV) as well as to the impact of the different beam parameters (modulation, collimation, field size etc.). Moreover, when compared with published data, the assessed secondary neutron doses showed similar trends, but sometimes with sensitive differences. This confirms secondary neutrons to be directly dependent on beam energy, modulation technique, treatment configuration and methodology.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
1_ASSA2030
Problema de saúde:
1_financiamento_saude
Assunto principal:
Craniofaringioma
/
Neoplasias Oculares
/
Terapia com Prótons
/
Melanoma
/
Nêutrons
Tipo de estudo:
Health_economic_evaluation
/
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Radiat Prot Dosimetry
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
França