Your browser doesn't support javascript.
loading
Lethal and sublethal effects of imidacloprid, after chronic exposure, on the insect model Drosophila melanogaster.
Charpentier, Gaël; Louat, Fanny; Bonmatin, Jean-Marc; Marchand, Patrice A; Vanier, Fanny; Locker, Daniel; Decoville, Martine.
Afiliação
  • Charpentier G; Centre de Biophysique Moléculaire, Centre National de la Recherche Scientifique, 45071 Orléans, France.
Environ Sci Technol ; 48(7): 4096-102, 2014 Apr 01.
Article em En | MEDLINE | ID: mdl-24588730
ABSTRACT
Neonicotinoids are subjected to vigilance because of environmental contaminations and deleterious effects on bees. Imidacloprid (IMI) is one of the most representative insecticides of this family. At chronic exposure, concentration-effect relationships are non linear. An insect model should allow a better description of this toxicity. We compared the lethal concentration 50% (LC50) of IMI for a Drosophila-field strain, after acute and chronic exposure. Relative to the acute LC50, the chronic LC50 was lowered by a factor of 29 for males (1.3 mM/45 µM), 52 for larvae (157 µM/3 µM) and more than 172 for females (>3.1 mM/18 µM). Chronic exposure also revealed significant lethal and sublethal effects, at concentrations 3-5 orders of magnitude lower than the chronic LC50. Mean mortalities reached 28% (at 3.91 nM) and 27% (at 39.1 nM) for females and males, respectively. Fecundity decreased of 16% at 1.96 nM. Mating increased of 30% at 0.391 nM. The LOEC (lowest observed effect concentration 0.391 nM) was 46 000 times lower than the chronic LC50 for males; it was 115 000 times lower than the chronic LC50 for females. This study illuminates effects that neonicotinoids can induce at very low concentrations. This is of particular interest for nontarget insects and for insect dependent species.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testes de Toxicidade / Drosophila melanogaster / Exposição Ambiental / Imidazóis / Inseticidas / Nitrocompostos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Environ Sci Technol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testes de Toxicidade / Drosophila melanogaster / Exposição Ambiental / Imidazóis / Inseticidas / Nitrocompostos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Environ Sci Technol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: França
...