Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase.

Frey, Avery G; Nandal, Anjali; Park, Jong Hwan; Smith, Pamela M; Yabe, Toshiki; Ryu, Moon-Suhn; Ghosh, Manik C; Lee, Jaekwon; Rouault, Tracey A; Park, Myung Hee; Philpott, Caroline C

Frey, Avery G; Nandal, Anjali; Park, Jong Hwan; Smith, Pamela M; Yabe, Toshiki; Ryu, Moon-Suhn; Ghosh, Manik C; Lee, Jaekwon; Rouault, Tracey A; Park, Myung Hee; Philpott, Caroline C.

Afiliação

Frey AG; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;
Nandal A; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;
Park JH; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892;
Smith PM; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;
Yabe T; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;
Ryu MS; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892;
Ghosh MC; Molecular Medicine Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and.
Lee J; Department of Biochemistry and Redox Biology Center, University of Nebraska, Lincoln, NE 68516.
Rouault TA; Molecular Medicine Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892; and.
Park MH; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892;
Philpott CC; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892; carolinep@intra.niddk.nih.gov.

Proc Natl Acad Sci U S A ; 111(22): 8031-6, 2014 Jun 03.

Article em En | MEDLINE | ID: mdl-24843120

Assuntos

Ferritinas/metabolismo; Ribonucleoproteínas Nucleares Heterogêneas/metabolismo; Ferro/metabolismo; Oxigenases de Função Mista/metabolismo; Proteínas de Ligação a RNA/metabolismo; Carcinoma Hepatocelular; Citosol/metabolismo; Proteínas de Ligação a DNA; Células HEK293; Heme/biossíntese; Ribonucleoproteínas Nucleares Heterogêneas/genética; Humanos; Proteínas Ferro-Enxofre/metabolismo; Neoplasias Hepáticas; Mitocôndrias/metabolismo; Chaperonas Moleculares/metabolismo; Fatores de Iniciação de Peptídeos/metabolismo; RNA Interferente Pequeno/genética; Proteínas de Ligação a RNA/genética; Fator de Iniciação de Tradução Eucariótico 5A

Palavras-chave

diiron enzyme; iron regulatory protein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a RNA / Ribonucleoproteínas Nucleares Heterogêneas / Ferritinas / Oxigenases de Função Mista / Ferro Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article

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