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CTSH regulates ß-cell function and disease progression in newly diagnosed type 1 diabetes patients.
Fløyel, Tina; Brorsson, Caroline; Nielsen, Lotte B; Miani, Michela; Bang-Berthelsen, Claus Heiner; Friedrichsen, Martin; Overgaard, Anne Julie; Berchtold, Lukas A; Wiberg, Anna; Poulsen, Pernille; Hansen, Lars; Rosinger, Silke; Boehm, Bernhard O; Ram, Ramesh; Nguyen, Quang; Mehta, Munish; Morahan, Grant; Concannon, Patrick; Bergholdt, Regine; Nielsen, Jens H; Reinheckel, Thomas; von Herrath, Matthias; Vaag, Allan; Eizirik, Decio Laks; Mortensen, Henrik B; Størling, Joachim; Pociot, Flemming.
Afiliação
  • Fløyel T; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark.
  • Brorsson C; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark.
  • Nielsen LB; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;
  • Miani M; Laboratory of Experimental Medicine, Université Libre de Bruxelles, 1070 Brussels, Belgium;
  • Bang-Berthelsen CH; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark.
  • Friedrichsen M; Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet, 2100 Copenhagen, Denmark;
  • Overgaard AJ; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark.
  • Berchtold LA; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark.
  • Wiberg A; Type 1 Diabetes Center, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037;
  • Poulsen P; Global Development, Novo Nordisk A/S, 2860 Søborg, Denmark;
  • Hansen L; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;
  • Rosinger S; Department of Internal Medicine, University of Ulm, 89081 Ulm, Germany;
  • Boehm BO; Department of Internal Medicine, University of Ulm, 89081 Ulm, Germany;Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore 637553;
  • Ram R; Centre for Diabetes Research, Western Australian Institute for Medical Research, University of Western Australia, Perth, WA 6000, Australia;
  • Nguyen Q; Centre for Diabetes Research, Western Australian Institute for Medical Research, University of Western Australia, Perth, WA 6000, Australia;
  • Mehta M; Centre for Diabetes Research, Western Australian Institute for Medical Research, University of Western Australia, Perth, WA 6000, Australia;
  • Morahan G; Centre for Diabetes Research, Western Australian Institute for Medical Research, University of Western Australia, Perth, WA 6000, Australia;
  • Concannon P; Genetics Institute, University of Florida, Gainesville, FL 32610;
  • Bergholdt R; Hagedorn Research Institute, Novo Nordisk, 2820 Gentofte, Denmark;
  • Nielsen JH; Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; and.
  • Reinheckel T; Institute of Molecular Medicine and Cell Research and Centre for Biological Signalling Studies, Albert Ludwigs University, 79085 Freiburg, Germany.
  • von Herrath M; Type 1 Diabetes Center, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037;
  • Vaag A; Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet, 2100 Copenhagen, Denmark;
  • Eizirik DL; Laboratory of Experimental Medicine, Université Libre de Bruxelles, 1070 Brussels, Belgium;
  • Mortensen HB; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;
  • Størling J; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark.
  • Pociot F; Department of Pediatrics, Herlev University Hospital, 2730 Herlev, Denmark;Glostrup Research Institute, Glostrup University Hospital, 2600 Glostrup, Denmark,Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; and flemming.pociot.01@regio
Proc Natl Acad Sci U S A ; 111(28): 10305-10, 2014 Jul 15.
Article em En | MEDLINE | ID: mdl-24982147
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 2_muertes_prevenibles / 6_diabetes / 6_endocrine_disorders Assunto principal: Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 / Células Secretoras de Insulina / Catepsina H Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adolescent / Animals / Child / Child, preschool / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 2_muertes_prevenibles / 6_diabetes / 6_endocrine_disorders Assunto principal: Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 / Células Secretoras de Insulina / Catepsina H Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adolescent / Animals / Child / Child, preschool / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Dinamarca