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Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria.
Lau, Clinton K Y; Turner, Louise; Jespersen, Jakob S; Lowe, Edward D; Petersen, Bent; Wang, Christian W; Petersen, Jens E V; Lusingu, John; Theander, Thor G; Lavstsen, Thomas; Higgins, Matthew K.
Afiliação
  • Lau CK; Department of Biochemistry, University of Oxford, South Parks Road, OX1 3QU Oxford, UK.
  • Turner L; Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, University of Copenhagen and Department of Infectious Diseases, Rigshospitalet, 1017 Copenhagen, Denmark.
  • Jespersen JS; Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, University of Copenhagen and Department of Infectious Diseases, Rigshospitalet, 1017 Copenhagen, Denmark.
  • Lowe ED; Department of Biochemistry, University of Oxford, South Parks Road, OX1 3QU Oxford, UK.
  • Petersen B; Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
  • Wang CW; Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, University of Copenhagen and Department of Infectious Diseases, Rigshospitalet, 1017 Copenhagen, Denmark.
  • Petersen JE; Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, University of Copenhagen and Department of Infectious Diseases, Rigshospitalet, 1017 Copenhagen, Denmark.
  • Lusingu J; National Institute for Medical Research, Tanga, 2448 Ocean Road, P.O. Box 9653, Dar es Salaan, Tanzania.
  • Theander TG; Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, University of Copenhagen and Department of Infectious Diseases, Rigshospitalet, 1017 Copenhagen, Denmark.
  • Lavstsen T; Centre for Medical Parasitology, Department of International Health, Immunology & Microbiology, University of Copenhagen and Department of Infectious Diseases, Rigshospitalet, 1017 Copenhagen, Denmark. Electronic address: thomasl@sund.ku.dk.
  • Higgins MK; Department of Biochemistry, University of Oxford, South Parks Road, OX1 3QU Oxford, UK. Electronic address: matthew.higgins@bioch.ox.ac.uk.
Cell Host Microbe ; 17(1): 118-29, 2015 Jan 14.
Article em En | MEDLINE | ID: mdl-25482433
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 3_ND Problema de saúde: 3_malaria / 3_neglected_diseases / 3_zoonosis Assunto principal: Variação Genética / Antígenos CD / Proteínas de Protozoários / Receptores de Superfície Celular / Interações Hospedeiro-Patógeno Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Cell Host Microbe Assunto da revista: MICROBIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 3_ND Problema de saúde: 3_malaria / 3_neglected_diseases / 3_zoonosis Assunto principal: Variação Genética / Antígenos CD / Proteínas de Protozoários / Receptores de Superfície Celular / Interações Hospedeiro-Patógeno Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Cell Host Microbe Assunto da revista: MICROBIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido