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A novel therapeutic strategy to rescue the immune effector function of proteolytically inactivated cancer therapeutic antibodies.
Fan, Xuejun; Brezski, Randall J; Deng, Hui; Dhupkar, Pooja M; Shi, Yun; Gonzalez, Anneliese; Zhang, Songlin; Rycyzyn, Michael; Strohl, William R; Jordan, Robert E; Zhang, Ningyan; An, Zhiqiang.
Afiliação
  • Fan X; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, Houston, Texas.
  • Brezski RJ; Biologics Research, Janssen R&D, LLC, Spring House, Pennsylvania.
  • Deng H; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, Houston, Texas.
  • Dhupkar PM; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, Houston, Texas.
  • Shi Y; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, Houston, Texas.
  • Gonzalez A; Division of Oncology, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, Texas.
  • Zhang S; Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston, Houston, Texas.
  • Rycyzyn M; Biologics Research, Janssen R&D, LLC, Spring House, Pennsylvania.
  • Strohl WR; Biologics Research, Janssen R&D, LLC, Spring House, Pennsylvania.
  • Jordan RE; Biologics Research, Janssen R&D, LLC, Spring House, Pennsylvania.
  • Zhang N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, Houston, Texas. zhiqiang.an@uth.tmc.edu ningyan.zhang@uth.tmc.edu.
  • An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, Houston, Texas. zhiqiang.an@uth.tmc.edu ningyan.zhang@uth.tmc.edu.
Mol Cancer Ther ; 14(3): 681-91, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25552368

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteólise / Anticorpos Monoclonais / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteólise / Anticorpos Monoclonais / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2015 Tipo de documento: Article
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