Risk factors associated to diabetes in Mexican population and phenotype of the individuals who will convert to diabetes.
Salud Publica Mex
; 56(4): 317-22, 2014.
Article
em En
| MEDLINE
| ID: mdl-25604171
ABSTRACT
OBJECTIVE:
To describe risk factors associated to the incidence of type 2 diabetes (T2D) in Mexican population and to define phenotypic (clinical, anthropometric, metabolic) characteristics present in the individual who will convert to diabetes, regardless of time of onset. MATERIALS ANDMETHODS:
The Mexico City Diabetes Study began in 1990, with 2 282 participants, and had three subsequent phases 1994, 1998, and 2008. A systematic evaluation with an oral glucose tolerance test was performed in each phase. For diagnosis of T2D, American Diabetes Association criteria were used.RESULTS:
The population at risk was 1939 individuals. Subjects who were in the converter stage (initially non diabetic that eventually converted to T2D) had, at baseline, higher BMI (30 vs 27), systolic blood pressure (119 vs 116 mmHg), fasting glucose (90 vs 82mg/dl), triglycerides (239 vs 196mg/dl), and cholesterol (192 vs 190mg/dl), compared with subjects who remained non converters (p<0.05).CONCLUSION:
The phenotype described represents a potentially identifiable phase and a target for preventive intervention.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Diabetes Mellitus Tipo 2
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
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Humans
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Male
/
Middle aged
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Salud Publica Mex
Ano de publicação:
2014
Tipo de documento:
Article