HLA types in patients with rheumatoid arthritis developing leucopenia after both gold and sulphasalazine treatment.
Ann Rheum Dis
; 48(7): 539-41, 1989 Jul.
Article
em En
| MEDLINE
| ID: mdl-2570550
ABSTRACT
HLA types, especially HLA-DR3, are associated with the development of toxic reactions in patients with rheumatoid arthritis after treatment with gold or D-penicillamine. In this study, after treatment with sulphasalazine, leucopenia was observed in three patients, who all had a history of leucopenia after previous gold treatment. The HLA types of these patients did not include HLA-DR3; the two patients developing mild leucopenia had HLA-DR2 and the one developing agranulocytosis had HLA-DR4.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Sulfassalazina
/
Antígenos HLA-DR
/
Tiomalato Sódico de Ouro
/
Leucopenia
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Ann Rheum Dis
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Dinamarca