Chronic Exposure to Excess Nutrients Left-shifts the Concentration Dependence of Glucose-stimulated Insulin Secretion in Pancreatic ß-Cells.

Erion, Karel A; Berdan, Charles A; Burritt, Nathan E; Corkey, Barbara E; Deeney, Jude T

Erion, Karel A; Berdan, Charles A; Burritt, Nathan E; Corkey, Barbara E; Deeney, Jude T.

Afiliação

Erion KA; From the Obesity Research Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118.
Berdan CA; From the Obesity Research Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118.
Burritt NE; From the Obesity Research Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118.
Corkey BE; From the Obesity Research Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118.
Deeney JT; From the Obesity Research Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118 jdeeney@bu.edu.

J Biol Chem ; 290(26): 16191-201, 2015 Jun 26.

Article em En | MEDLINE | ID: mdl-25934392

Assuntos

Glucose/metabolismo; Insulina/metabolismo; Ilhotas Pancreáticas/metabolismo; Animais; Cálcio/metabolismo; Linhagem Celular; Células Cultivadas; Exocitose; Secreção de Insulina; Células Secretoras de Insulina/metabolismo; Masculino; Ratos; Ratos Sprague-Dawley

Palavras-chave

beta cell (ß-cell); calcium imaging; hyperinsulinemia; insulin secretion; lipid; metabolism; type 2 diabetes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Glucose / Insulina Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article

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