[Rotavirus infection: epidemiology, pathology, vaccination].
Vestn Ross Akad Med Nauk
; (1): 47-55, 2015.
Article
em Ru
| MEDLINE
| ID: mdl-26027271
ABSTRACT
Diarrheal infections remain the major cause of morbidity and mortality among children under 5 years of age. The rotavirus holds the leading position among principal diarrheal pathogens that include also norovirus, enteropathogenic and enterotoxigenic Escherichia coli. Rotaviruses are transmitted by the fecal-oral route and are extremely contagious and stable in the environment. This facilitates viral transmission, particularly in daycare centers and hospitals. Rotavirus infection causes acute gastroenteritis with diarrhea and dehydration of various degrees resulting primarily from destruction of intestinal villus enterocytes with subsequent impairment of the ion transport and absorption. The incidence of rotavirus infection peaks during the winter and spring in countries with temperate climate. Many children have asymptomatic infection that supports rotavirus circulation in the popula- tion. Several vaccines have been developed for specific prophylaxis of rotavirus infections and demonstrated protection from severe acute rotavirus gastroenteritis and all-cause diarrheal mortality.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
/
3_ND
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4_TD
/
7_ODS3_muertes_prevenibles_nacidos_ninos
Problema de saúde:
1_doencas_transmissiveis
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2_cobertura_universal
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2_enfermedades_transmissibles
/
2_muertes_prevenibles
/
3_diarrhea
/
3_neglected_diseases
/
4_diarrhoeal_infections
/
7_environmental_health
/
7_infections
Assunto principal:
Infecções por Rotavirus
/
Rotavirus
/
Vacinas contra Rotavirus
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
Ru
Revista:
Vestn Ross Akad Med Nauk
Assunto da revista:
MEDICINA
Ano de publicação:
2015
Tipo de documento:
Article