A chiral HPLC-MS/MS method for simultaneous quantification of warfarin enantiomers and its major hydroxylation metabolites of CYP2C9 and CYP3A4 in human plasma.

Ju, W; Peng, K; Yang, S; Sun, H; Sampson, M; Wang, M Z

Ju, W; Peng, K; Yang, S; Sun, H; Sampson, M; Wang, M Z.

Afiliação

Ju W; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, USA.
Peng K; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, USA.
Yang S; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, USA.
Sun H; Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sampson M; Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wang MZ; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, USA.

Austin J Anal Pharm Chem ; 1(2)2014.

Article em En | MEDLINE | ID: mdl-26161443

Palavras-chave

Chiral Separation; HPLC-MS/MS; Hydroxywarfarin; Protein precipitation extraction; Warfarin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Austin J Anal Pharm Chem Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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