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Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC).
Zheng, Jie; van de Veerdonk, Frank L; Crossland, Katherine L; Smeekens, Sanne P; Chan, Chun M; Al Shehri, Tariq; Abinun, Mario; Gennery, Andrew R; Mann, Jelena; Lendrem, Dennis W; Netea, Mihai G; Rowan, Andrew D; Lilic, Desa.
Afiliação
  • Zheng J; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • van de Veerdonk FL; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
  • Crossland KL; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Smeekens SP; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
  • Chan CM; Musculoskeletal Research Group, Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Al Shehri T; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Abinun M; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Gennery AR; Department of Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne, UK.
  • Mann J; Primary Immune Deficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Lendrem DW; Department of Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne, UK.
  • Netea MG; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Rowan AD; Musculoskeletal Research Group, Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
  • Lilic D; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
Eur J Immunol ; 45(10): 2834-46, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26255980

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Candidíase Mucocutânea Crônica / Regulação da Expressão Gênica / Fator de Transcrição STAT1 / Fator de Transcrição STAT3 / Mutação Limite: Female / Humans / Male Idioma: En Revista: Eur J Immunol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Candidíase Mucocutânea Crônica / Regulação da Expressão Gênica / Fator de Transcrição STAT1 / Fator de Transcrição STAT3 / Mutação Limite: Female / Humans / Male Idioma: En Revista: Eur J Immunol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido
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