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The spliceosome is a therapeutic vulnerability in MYC-driven cancer.
Hsu, Tiffany Y-T; Simon, Lukas M; Neill, Nicholas J; Marcotte, Richard; Sayad, Azin; Bland, Christopher S; Echeverria, Gloria V; Sun, Tingting; Kurley, Sarah J; Tyagi, Siddhartha; Karlin, Kristen L; Dominguez-Vidaña, Rocio; Hartman, Jessica D; Renwick, Alexander; Scorsone, Kathleen; Bernardi, Ronald J; Skinner, Samuel O; Jain, Antrix; Orellana, Mayra; Lagisetti, Chandraiah; Golding, Ido; Jung, Sung Y; Neilson, Joel R; Zhang, Xiang H-F; Cooper, Thomas A; Webb, Thomas R; Neel, Benjamin G; Shaw, Chad A; Westbrook, Thomas F.
Afiliação
  • Hsu TY; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Simon LM; Interdepartmental Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Neill NJ; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Marcotte R; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Sayad A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Bland CS; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Echeverria GV; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Sun T; Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2C4, Canada.
  • Kurley SJ; Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2C4, Canada.
  • Tyagi S; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Karlin KL; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Dominguez-Vidaña R; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Hartman JD; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Renwick A; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Scorsone K; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Bernardi RJ; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Skinner SO; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Jain A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Orellana M; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Lagisetti C; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Golding I; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Jung SY; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Neilson JR; Verna &Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Zhang XH; Interdepartmental Program in Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Cooper TA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Webb TR; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Neel BG; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Shaw CA; Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Westbrook TF; Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.
Nature ; 525(7569): 384-8, 2015 Sep 17.
Article em En | MEDLINE | ID: mdl-26331541
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Genes myc / Spliceossomos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Nature Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Genes myc / Spliceossomos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Nature Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos