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A High-Throughput Screen to Identify LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease Using RapidFire Mass Spectrometry.
Leveridge, Melanie; Collier, Lee; Edge, Colin; Hardwicke, Phil; Leavens, Bill; Ratcliffe, Steve; Rees, Mike; Stasi, Luigi Piero; Nadin, Alan; Reith, Alastair D.
Afiliação
  • Leveridge M; Department of Platform Technology and Science, GlaxoSmithKline Pharmaceuticals R&D, Hertfordshire, UK melanie.v.leveridge@gsk.com.
  • Collier L; Department of Platform Technology and Science, GlaxoSmithKline Pharmaceuticals R&D, Hertfordshire, UK Cancer Research Technology, Babraham Research Campus, Cambridge, UK.
  • Edge C; Department of Platform Technology and Science, GlaxoSmithKline Pharmaceuticals R&D, Hertfordshire, UK.
  • Hardwicke P; Department of Platform Technology and Science, GlaxoSmithKline Pharmaceuticals R&D, Hertfordshire, UK.
  • Leavens B; Department of Platform Technology and Science, GlaxoSmithKline Pharmaceuticals R&D, Hertfordshire, UK.
  • Ratcliffe S; Department of Platform Technology and Science, GlaxoSmithKline Pharmaceuticals R&D, Hertfordshire, UK.
  • Rees M; Department of Platform Technology and Science, GlaxoSmithKline Pharmaceuticals R&D, Hertfordshire, UK.
  • Stasi LP; Neurodegeneration DPU, Neurosciences Therapy Area Unit, GlaxoSmithKline, Pharmaceuticals R&D, Hertfordshire, UK, and Pudong, China Nuevolution A/S, Rønnegade 8, DK-2100 Copenhagen, Denmark.
  • Nadin A; Department of Platform Technology and Science, GlaxoSmithKline Pharmaceuticals R&D, Hertfordshire, UK.
  • Reith AD; Neurodegeneration DPU, Neurosciences Therapy Area Unit, GlaxoSmithKline, Pharmaceuticals R&D, Hertfordshire, UK, and Pudong, China.
J Biomol Screen ; 21(2): 145-55, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26403521
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas Serina-Treonina Quinases / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biomol Screen Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas Serina-Treonina Quinases / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biomol Screen Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido