Exposure to 3,3',5-triiodothyronine affects histone and RNA polymerase II modifications, but not DNA methylation status, in the regulatory region of the Xenopus laevis thyroid hormone receptor ß&#913; gene.

Kasai, Kentaro; Nishiyama, Norihito; Izumi, Yushi; Otsuka, Shunsuke; Ishihara, Akinori; Yamauchi, Kiyoshi

Exposure to 3,3',5-triiodothyronine affects histone and RNA polymerase II modifications, but not DNA methylation status, in the regulatory region of the Xenopus laevis thyroid hormone receptor ßΑ gene.

Kasai, Kentaro; Nishiyama, Norihito; Izumi, Yushi; Otsuka, Shunsuke; Ishihara, Akinori; Yamauchi, Kiyoshi.

Afiliação

Kasai K; Department of Biological Science, Graduate School of Science, Shizuoka University, Shizuoka 422-8529, Japan.
Nishiyama N; Department of Natural Sciences (Biology), School of Medicine, Fukushima Medical University, Fukushima 960-1295, Japan.
Izumi Y; Department of Biological Science, Graduate School of Science, Shizuoka University, Shizuoka 422-8529, Japan.
Otsuka S; Department of Biological Science, Graduate School of Science, Shizuoka University, Shizuoka 422-8529, Japan.
Ishihara A; Department of Biological Science, Graduate School of Science, Shizuoka University, Shizuoka 422-8529, Japan; Green Biology Research Division, Research Institute of Green Science and Technology, Shizuoka University, Shizuoka 422-8529, Japan.
Yamauchi K; Department of Biological Science, Graduate School of Science, Shizuoka University, Shizuoka 422-8529, Japan; Green Biology Research Division, Research Institute of Green Science and Technology, Shizuoka University, Shizuoka 422-8529, Japan. Electronic address: yamauchi.kiyoshi@shizuoka.ac.jp.

Biochem Biophys Res Commun ; 467(1): 33-8, 2015 Nov 06.

Article em En | MEDLINE | ID: mdl-26417689

Assuntos

Receptores beta dos Hormônios Tireóideos/genética; Tri-Iodotironina/farmacologia; Proteínas de Xenopus/genética; Xenopus laevis/genética; Xenopus laevis/metabolismo; Animais; Metilação de DNA; Histonas/metabolismo; RNA Polimerase II/metabolismo; Sequências Reguladoras de Ácido Nucleico; Proteínas de Xenopus/metabolismo

Palavras-chave

DNA methylation; Histone modification; Thyroid hormone; Thyroid hormone receptor gene; Xenopus laevis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tri-Iodotironina / Xenopus laevis / Proteínas de Xenopus / Receptores beta dos Hormônios Tireóideos Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão

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