Experimental infection of peridomestic mammals with emergent H7N9 (A/Anhui/1/2013) influenza A virus: Implications for biosecurity and wet markets.
Virology
; 487: 242-8, 2016 Jan.
Article
em En
| MEDLINE
| ID: mdl-26550948
ABSTRACT
During 2013, a novel avian-origin H7N9 influenza A virus (IAV) emerged in China and subsequently caused large economic and public health burdens. We experimentally infected three common peridomestic wild mammals with H7N9 (A/Anhui/1/2013) IAV. Striped skunks exhibited the highest burden of disease followed by raccoons and cottontail rabbits. Striped skunks also produced the highest levels of viral shedding (up to 10(6.4)PFU/mL nasal flush) followed by cottontail rabbits (up to 10(5.8)PFU/mL nasal flush) and raccoons (up to 10(5.2)PFU/mL nasal flush). Thus, various mammalian species, especially those that are peridomestic, could play a role in the epidemiology of emergent H7N9 IAV. Mammals should be accounted for in biosecurity plans associated with H7N9 and their presence in wet markets, dependent on species, could lead to increased transmission among interspecific species aggregations and may also pose an elevated zoonotic disease risk to visitors and workers of such markets.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
2_ODS3
Problema de saúde:
2_enfermedades_transmissibles
Assunto principal:
Zoonoses
/
Infecções por Orthomyxoviridae
/
Subtipo H7N9 do Vírus da Influenza A
/
Animais Selvagens
Limite:
Animals
País/Região como assunto:
Asia
Idioma:
En
Revista:
Virology
Ano de publicação:
2016
Tipo de documento:
Article