A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines.

Suschak, John J; Wang, Shixia; Fitzgerald, Katherine A; Lu, Shan

Suschak, John J; Wang, Shixia; Fitzgerald, Katherine A; Lu, Shan.

Afiliação

Suschak JJ; Laboratory of Nucleic Acid Vaccines, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655; and.
Wang S; Laboratory of Nucleic Acid Vaccines, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655; and.
Fitzgerald KA; Program in Innate Immunity, Division of Infectious Diseases, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655.
Lu S; Laboratory of Nucleic Acid Vaccines, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655; and shan.lu@umassmed.edu.

J Immunol ; 196(1): 310-6, 2016 Jan 01.

Article em En | MEDLINE | ID: mdl-26590319

Assuntos

Imunidade Inata/imunologia; Fator Regulador 7 de Interferon/metabolismo; Proteínas de Membrana/metabolismo; Nucleotidiltransferases/metabolismo; Vacinas de DNA/imunologia; Animais; Linfócitos B/imunologia; Células Cultivadas; Fator Regulador 3 de Interferon/genética; Fator Regulador 3 de Interferon/metabolismo; Fator Regulador 7 de Interferon/genética; Proteínas de Membrana/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Nucleotidiltransferases/genética; Transdução de Sinais/imunologia; Linfócitos T/imunologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas de DNA / Fator Regulador 7 de Interferon / Imunidade Inata / Proteínas de Membrana / Nucleotidiltransferases Limite: Animals Idioma: En Revista: J Immunol Ano de publicação: 2016 Tipo de documento: Article

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