HLA-C and KIR combined genotype as new response marker for HBeAg-positive chronic hepatitis B patients treated with interferon-based combination therapy.

Stelma, F; Jansen, L; Sinnige, M J; van Dort, K A; Takkenberg, R B; Janssen, H L A; Reesink, H W; Kootstra, N A

Stelma, F; Jansen, L; Sinnige, M J; van Dort, K A; Takkenberg, R B; Janssen, H L A; Reesink, H W; Kootstra, N A.

Afiliação

Stelma F; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands.
Jansen L; Department of Experimental Immunology, Academic Medical Center, Amsterdam, the Netherlands.
Sinnige MJ; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands.
van Dort KA; Department of Experimental Immunology, Academic Medical Center, Amsterdam, the Netherlands.
Takkenberg RB; Department of Experimental Immunology, Academic Medical Center, Amsterdam, the Netherlands.
Janssen HL; Department of Experimental Immunology, Academic Medical Center, Amsterdam, the Netherlands.
Reesink HW; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands.
Kootstra NA; Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, the Netherlands.

J Viral Hepat ; 23(8): 652-9, 2016 08.

Article em En | MEDLINE | ID: mdl-26945896

Assuntos

Antivirais/uso terapêutico; Antígenos HLA-C/genética; Antígenos E da Hepatite B/sangue; Hepatite B Crônica/tratamento farmacológico; Hepatite B Crônica/genética; Interferons/uso terapêutico; Receptores KIR2DL1/genética; Adulto; Biomarcadores/análise; Quimioterapia Combinada/métodos; Feminino; Hepatite B Crônica/diagnóstico; Humanos; Masculino; Pessoa de Meia-Idade; Prognóstico; Resultado do Tratamento

Palavras-chave

HLA-C; Hepatitis B; KIR; NK cell; combination therapy; peg-interferon-alfa

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 Problema de saúde: 2_enfermedades_transmissibles Assunto principal: Antivirais / Antígenos HLA-C / Interferons / Hepatite B Crônica / Receptores KIR2DL1 / Antígenos E da Hepatite B Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Viral Hepat Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda

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