Quantitative analysis of ripasudil hydrochloride hydrate and its impurities by reversed-phase high-performance liquid chromatography after precolumn derivatization: Identification of four impurities.

Hui, Wenkai; Sun, Lili; Zhang, Hui; Zou, Liang; Zou, Qiaogen; Ouyang, Pingkai

Hui, Wenkai; Sun, Lili; Zhang, Hui; Zou, Liang; Zou, Qiaogen; Ouyang, Pingkai.

Afiliação

Hui W; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, P. R. China.
Sun L; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, P. R. China.
Zhang H; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, P. R. China.
Zou L; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, P. R. China.
Zou Q; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, P. R. China. qiaogenzou@hotmail.com.
Ouyang P; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, P. R. China.

J Sep Sci ; 39(17): 3302-10, 2016 Sep.

Article em En | MEDLINE | ID: mdl-27390135

Assuntos

Cromatografia de Fase Reversa/métodos; Isoquinolinas/química; Isotiocianatos/química; Inibidores de Proteínas Quinases/química; Sulfonamidas/química; Cromatografia Líquida de Alta Pressão/métodos

Palavras-chave

Impurities; Precolumn derivatization; Quantitative analysis; Ripasudil hydrochloride hydrate

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Isotiocianatos / Inibidores de Proteínas Quinases / Cromatografia de Fase Reversa / Isoquinolinas Tipo de estudo: Diagnostic_studies / Evaluation_studies Idioma: En Revista: J Sep Sci Ano de publicação: 2016 Tipo de documento: Article

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