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Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.
Burgess, Selena G; Oleksy, Arkadiusz; Cavazza, Tommaso; Richards, Mark W; Vernos, Isabelle; Matthews, David; Bayliss, Richard.
Afiliação
  • Burgess SG; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 9HN, UK.
  • Oleksy A; Centre for Therapeutics Discovery, MRC Technology, The Accelerator Building, Stevenage, Bioscience Catalyst, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2FX, UK.
  • Cavazza T; Cell and Developmental Biology program, Centre for Genomic Regulation (CRG) and UPF, Dr Aiguader 88, 08003 Barcelona, Spain.
  • Richards MW; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 9HN, UK.
  • Vernos I; Cell and Developmental Biology program, Centre for Genomic Regulation (CRG) and UPF, Dr Aiguader 88, 08003 Barcelona, Spain Institució Catalana de Recerca i Estudis Avançats (ICREA), Pg. Lluis Companys 23, 08010 Barcelona, Spain.
  • Matthews D; Centre for Therapeutics Discovery, MRC Technology, The Accelerator Building, Stevenage, Bioscience Catalyst, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2FX, UK.
  • Bayliss R; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 9HN, UK r.w.bayliss@leeds.ac.uk.
Open Biol ; 6(7)2016 07.
Article em En | MEDLINE | ID: mdl-27411893
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos de Domínio Único / Aurora Quinase A Limite: Humans Idioma: En Revista: Open Biol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos de Domínio Único / Aurora Quinase A Limite: Humans Idioma: En Revista: Open Biol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido