Stimulation of Natural Killer Cell-Mediated Tumor Immunity by an IL15/TGFß-Neutralizing Fusion Protein.

Ng, Spencer; Deng, Jiusheng; Chinnadurai, Raghavan; Yuan, Shala; Pennati, Andrea; Galipeau, Jacques

Ng, Spencer; Deng, Jiusheng; Chinnadurai, Raghavan; Yuan, Shala; Pennati, Andrea; Galipeau, Jacques.

Afiliação

Ng S; Department of Hematology and Medical Oncology, School of Medicine, Emory University, Atlanta, Georgia. Winship Cancer Institute, Emory University, Atlanta, Georgia.
Deng J; Department of Hematology and Medical Oncology, School of Medicine, Emory University, Atlanta, Georgia. Winship Cancer Institute, Emory University, Atlanta, Georgia.
Chinnadurai R; Department of Hematology and Medical Oncology, School of Medicine, Emory University, Atlanta, Georgia. Winship Cancer Institute, Emory University, Atlanta, Georgia.
Yuan S; Department of Hematology and Medical Oncology, School of Medicine, Emory University, Atlanta, Georgia. Winship Cancer Institute, Emory University, Atlanta, Georgia.
Pennati A; Department of Hematology and Medical Oncology, School of Medicine, Emory University, Atlanta, Georgia. Winship Cancer Institute, Emory University, Atlanta, Georgia.
Galipeau J; Department of Hematology and Medical Oncology, School of Medicine, Emory University, Atlanta, Georgia. Winship Cancer Institute, Emory University, Atlanta, Georgia. Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia. Jgalipe@emory.edu.

Cancer Res ; 76(19): 5683-5695, 2016 10 01.

Article em En | MEDLINE | ID: mdl-27488533

Assuntos

Interleucina-15/farmacologia; Células Matadoras Naturais/efeitos dos fármacos; Neoplasias/tratamento farmacológico; Proteínas Recombinantes de Fusão/farmacologia; Fator de Crescimento Transformador beta/farmacologia; Animais; Linfócitos T CD8-Positivos/efeitos dos fármacos; Linfócitos T CD8-Positivos/imunologia; Linhagem Celular Tumoral; Humanos; Células Matadoras Naturais/imunologia; Ativação Linfocitária/efeitos dos fármacos; Camundongos; Camundongos Endogâmicos C57BL; Neoplasias/imunologia; Microambiente Tumoral

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Células Matadoras Naturais / Fator de Crescimento Transformador beta / Interleucina-15 / Neoplasias Limite: Animals / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Geórgia

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